Hif3a CLIA Kit for Rat(Rattus norvegicus) | EIAab.comHif3a CLIA Kit for Rat(Rattus norvegicus)

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Hif3a (Gene name),

Hypoxia-inducible factor 3-alpha (Protein name ), HIF3A_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Hif3a;

Protein name:

Hypoxia-inducible factor 3-alpha(HIF-3-alpha;HIF3-alpha);

Alternative:

HIF3-alpha-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterodimerizes with ARNT. Interacts via the oxygen-dependent degradation domain (ODD) with the beta domain of VHL.

Function:

Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE.

Subcellular Location:

Nucleus Cytoplasm In the nuclei of all periportal and perivenous hepatocytes. In the distal perivenous zone, detected in the cytoplasm of the hepatocytes.

Protein Attributes:

Sequence length:

662

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

662:

HFLPAAGLAQ | TH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF11413

STRING:

10116.ENSRNOP00000062542

String:

Q9JHS2

KEGG:

rno:64345

UniGene:

Rn.161814

Uniprot:

Q9JHS2

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ELISA Kit for Rat HIF-3-alpha

Cat.:

E10271h

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96T

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ELISA Kit for Rat HIF-3-alpha

Cat.:

E10271r

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96T

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ELISA Kit for Rat HIF-3-alpha

Cat.:

E10271m

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Packing:

96T

CLIA Kit for Rat HIF-3-alpha

Cat.:

U10271m

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MSDS:

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Packing:

96T

CLIA Kit for Rat HIF-3-alpha

Cat.:

U10271h

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MSDS:

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Packing:

96T

CLIA Kit for Rat HIF-3-alpha

Cat.:

U10271r

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Packing:

96T

Polyclonal Antibody for Rat HIF-3-alpha

Cat.:

P10271Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat HIF-3-alpha

Cat.:

P10271Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat HIF-3-alpha

Cat.:

P10271Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat HIF-3-alpha

Protein for Rat HIF-3-alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver."
Kietzmann T. , Cornesse Y. , Brechtel K. , Modaressi S. , Jungermann K.
Biochem. J.354:531-537(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Liver.
2.

"Hypoxia rapidly activates HIF-3alpha mRNA expression."
Heidbreder M. , Froehlich F. , Johren O. , Dendorfer A. , Qadri F. , Dominiak P.
FASEB J.17:1541-1543(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

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